Overview

Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them. Senolytic compounds selectively target senescent cells.

Black tea theaflavins, apigenin, quercetin and fisetin all target different biological pathways, helping to manage senescent cells.

Senolytic Activator Benefits

• Helps the body manage senescent cells

• Promotes youthful, healthy cellular function

• Supports systemic rejuvenation

• Made with black tea theaflavins, apigenin,  and fisetin

• Convenient once-a-week dosing

Ultra-absorbable  Fisetin

These two plant flavonoids have many health benefits, but traditional forms are hard to absorb. So we use  fisetin that are encased in a phytosome sphere, aiding in their absorption and making them much, much more bioavailable. The plant-based flavonoid apigenin is included since it complements the senolytic activity of  black tea compounds.

Product Details

Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them.

Senolytic compounds selectively target senescent cells.  New research indicates that black tea theaflavins  target specific biological pathways, making it easier for the body to manage senescent cells.

Theaflavins reduce senescent cell burden

Theaflavins are compounds derived from Camellia sinensis (tea plant). These compounds have widespread health benefits, supporting healthy cell division and healthy inflammatory response.

New research indicates that theaflavins may be especially helpful for reducing senescent cell burden. In pre-clinical models, theaflavins helped powerfully inhibit the accumulation of particular cell senescence biomarkers.

Easy-to-absorb fisetin to boost longevity at the cellular level

Fisetin is terrific for whole-body health. It’s a powerful senolytic compound, meaning it actively target senescent cells, the ones that no longer function optimally. Fisetin helps encourage the body’s natural pathways for clearing senescent cells, which allows healthy cells to flourish.

Another important aspect of cellular longevity is sirtuin function. Sirtuin proteins keep your cells performing at their best—but sirtuin activity declines with age.  Fisetin has been shown in preclinical studies to encourage youthful, healthy sirtuin function.

But during digestion, much of fisetin is rapidly converted into other compounds by a process called conjugation. That’s why we protected fisetin by combining it with galactomannans, a type of fiber derived from fenugreek seed. Doing so makes it up to 25 times more readily available than standard fisetin. That means it circulates in your system longer and your body has more time to access fisetin’s many health benefits.

Apigenin

Life Extension has identified apigenin, a natural flavonoid, as a powerful addition to our Senolytic Activator® formula. Theaflavins from black tea target senescent cells, but not all of them.

The remaining senescent cells create compounds known collectively as Senescence Associated Secretory Phenotype, or SASP.  Apigenin helps inhibit remaining senescent cells from making SASP to support cellular and tissue health—a critical aspect of healthy aging.

Convenient, once-weekly formula

For those who aren’t keen on adding another supplement to their regimen, here’s good news: Senolytic research indicates that intermittent dosing in pre-clinical studies is effective at supporting healthspan. So, Senolytic Activator® instructions call for taking just three vegetarian capsules, once a week.

Manage senescent cells, promote healthy cellular function and support overall longevity with Senolytic Activator®.

Warnings

•      KEEP OUT OF REACH OF CHILDREN
•     DO NOT EXCEED RECOMMENDED DOSE

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Disclaimer

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

( This Product Description Is For Information Purposes Only. Always Check The Actual Product Label In Your Possession For The Most Accurate Ingredient Information Before Use. For Any Health Or Dietary Related Matter Always Consult Your Doctor Before Use.)