Ren Skincare Bio Retinoidâ„¢ Youth Cream treats visible lines and wrinkles by lifting and plumping the skin while boosting natural collagen production in the face. The Bio Retinoidâ„¢ Youth Cream is formulated with Bidens Pilosa, a plant-based alternative to retinol that is clinically proven to create visibly firmer, more supple skin after just 28 days of regular use. This natural cream contains ingredients like Red Algae Extract to visibly lift the skin while other natural ingredients protect from free radical damage that can further cause aging.